Spectrum of allergens for Japanese cedar pollinosis and impact of component-resolved diagnosis on allergen-specific immunotherapy
نویسندگان
چکیده
منابع مشابه
Biomarkers for allergen immunotherapy in cedar pollinosis.
To initiate, monitor, and complete effective immunotherapy, biomarkers to predict and visualize the immune responses are needed. First, we need to identify the right candidate for immunotherapy. Secondly, the immune responses induced by immunotherapy should be monitored. For the first objective, analysis of polymorphisms of candidate genes may be helpful, but still be in development. Regarding ...
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Sublingual immunotherapy is much safer than conventional percutaneous immunotherapy. This is the only treatment available which can completely cure the disease. A randomized, placebocontrolled, double-blind study has revealed that sublingual immunotherapy is both effective and safe for the patient with this pollinosis [3]. Only recently, standardized Japanese cedar pollen extract became availab...
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Allergic diseases are among the most common health issues worldwide. Specific immunotherapy has remained the only disease-modifying treatment, but it is not effective in all patients and may cause side effects. Over the last 25 years, allergen molecules from most prevalent allergen sources have been isolated and produced as recombinant proteins. Not only are these molecules useful in improved a...
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In Japan, Japanese cedar pollinosis (JCP) is one of the most prevalent forms of seasonal allergic rhinitis (AR). The JC pollen scattering period starts at the beginning of February and finishes at the end of April. JCP and asthma present concurrently; a previous survey showed that the prevalence of JCP in patients with asthma might be up to 30%--50%. Moreover, JCP is often associated with exace...
متن کاملComponent-resolved diagnosis-assisted prescription of allergen-specific immunotherapy: a practical guide.
Allergen specific immunotherapy remains the only means to change the natural history of allergic disease. Thanks to the recent advances in molecular biology a large spectrum of purified allergen molecules are presently routinely available for diagnostic purposes. This review represents a practical guide on how to use these new diagnostic tools in order to detect precisely the primary sensitizin...
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ژورنال
عنوان ژورنال: Allergology International
سال: 2015
ISSN: 1323-8930
DOI: 10.1016/j.alit.2015.05.008